Validate predictive biomarkers in cell lines

Plotter

1. Select gene or hallmark / KEGG pathway

Gene(s) Hallmark/KEGG pathway

2. Select treatment

Anticancer agents or

FDA approved drugs or

All available treatments

3. Response:

Responses based on lower and upper tertiles of AUDRC Responses based on lower and upper tertiles of IC50

4. Settings

Tissue of origin

Export cell line sensitivity rank as text file

No outliers

Show quartiles

Signature

Please kindly cite our paper to support further development: Janos Fekete, Balazs Gyorffy: A unified platform enabling biomarker ranking and validation for 1562 drugs using transcriptomic data of 1250 cancer cell lines, Computational and Structural Biotechnology Journal, 2022, 20:2885-2894, doi: 10.1016/j.csbj.2022.06.007.

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Results

Please run the analysis first

Adrenal Cancer
Bile Duct Cancer
Bladder Cancer
Bone Cancer
Brain Cancer
Breast Cancer
Cervical Cancer
Colon/ Colorectal Cancer
Embryonal Cancer
Endometrial/ Uterine Cancer
Esophageal Cancer
Fibroblast
Gallbladder Cancer
Gastric Cancer
Head And Neck Cancer
Kidney Cancer
Leukemia
Liposarcoma
Liver Cancer
Lung Cancer
Lymphoma
Myeloma
Neuroblastoma
Non Cancerous
Ovarian Cancer
Pancreatic Cancer
Prostate Cancer
Rhabdoid
Sarcoma
Skin Cancer
Thyroid Cancer
Unknown
Solid tumors