Validate predictive biomarkers in cell lines

1. Select gene or hallmark / KEGG pathway

Gene(s) Hallmark/KEGG pathway

 

 

2. Select treatment

Anticancer agents or

 

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FDA approved drugs or

 

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All available treatments

 

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3. Response:

Responses based on lower and upper tertiles of AUDRC Responses based on lower and upper tertiles of IC50

4. Settings

Tissue of origin Adrenal Cancer Bile Duct Cancer Bladder Cancer Bone Cancer Brain Cancer Breast Cancer Cervical Cancer Colon/colorectal Cancer Embryonal Cancer Endometrial/uterine Cancer Esophageal Cancer Fibroblast Gallbladder Cancer Gastric Cancer Head And Neck Cancer Kidney Cancer Leukemia Liposarcoma Liver Cancer Lung Cancer Lymphoma Myeloma Neuroblastoma Non Cancerous Ovarian Cancer Pancreatic Cancer Prostate Cancer Rhabdoid Sarcoma Skin Cancer Thyroid Cancer Unknown Solid tumors

Export cell line sensitivity rank as text file

No outliers

Show quartiles

Multi-gene analysis

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Please kindly cite our paper to support further development: Janos Fekete, Balazs Gyorffy: A unified platform enabling biomarker ranking and validation for 1562 drugs using transcriptomic data of 1250 cancer cell lines, Computational and Structural Biotechnology Journal, 2022, 20:2885-2894, doi: 10.1016/j.csbj.2022.06.007.